Spermatogenesis is the process by which spermatogonia in seminiferous tubules of testes develop into sperm that can leave the
male’s body
✍️ At p*berty, diploid germinal epithelial cells (primordial germ cells) of seminiferous tubules undergo
repeated mitotic divisions to form a number of diploid spermatogonia.
✍️Each spermatogonium increases in size and becomes a primary spermatocyte
✍️Each primary spermatocyte undergoes the first meiotic division to form two haploid secondary
spermatocytes, which undergo second meiotic division to form four haploid spermatids, connected to
each other by cytoplasm.
The spermatids get embedded into sertoli cells (loosely called “nurse cells”) to be transformed into sperm
by:
i) Losing part of cytoplasm
ii) Condensation of nucleus into head.
iii) Formation of flagellated tail.
The mature spermatozoa (sperms) finally detach from sertoli cells and are released into the lumen of
seminiferous tubules.